DESCRIPTION
Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important role in the body’s natural defence mechanisms. It stimulates synthesis and release of surfactant by type II pneumocytes. Surfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.
An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.
SIDE EFFECTS
Stomach upset symptoms can become uncomfortable and may contribute to a decreased appetite in certain patients. To limit the development of these side effects, ambroxol hydrochloride should be taken with food. Patients who experience severe nausea or vomiting while taking this medication should contact a doctor.
Less serious guaifenesin side effects may include:
- dizziness or headache,
- a rash, or.
- nausea, vomiting, or stomach upset.
INDICATION
Ambroxol is indicated as “secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport. It promotes mucus clearance, facilitates expectoration and eases productive cough, allowing patients to breathe freely and deeply.
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
For the prevention and reversal of bronchospasm in patients 12 years of age and older with reversible, obstructive airway disease, as well as symptomatic management of reversible bronchospasm associated with bronchitis and emphysema. Also used acute IV and sub-Q therapy in selected women to inhibit uterine contractions in preterm labor (tocolysis) and prolong gestation when beneficial.
